Many people are now acknowledging that the popular supplement called Niagen boosts the production and health of an enzyme that’s essential to our cells, called Nicotinamide Adenine Dinucleotide (NAD+). Niagen has numerous other health benefits too! But in this article, we’ll focus on the effects Niagen has on NAD+ levels.
The amount of NAD+ that’s the most beneficial to most people is from 250mg to 500mg daily, which can be difficult if you don’t know where to look. Luckily, Live Cell Research—a multi-national corporation—is marketing nicotinamide riboside under the brand NIAGEN. nicotinamide riboside is a type of vitamin B3 that was discovered recently. It helps the body in synthesizing Nicotinamide Adenine Dinucleotide.
Why exactly is NAD+?
This is an essential enzyme used by mitochondria in utilizing energy. Mitochondria are energy-producing organelle of the cell. NAD+ is naturally produced in the body. It is responsible for passing messages between the nucleus and mitochondria, where the nucleus gets its energy from.
With aging, our bodies produce less NAD+ and the communication between nucleus and mitochondria is impaired. The nucleus is no longer able to ask for sufficient energy. As a result of this, less energy is produced by the mitochondria, which is why the older you get, the more prone you are to illness.
How was nicotinamide riboside discovered?
It was observed that individuals suffering from myopathy had lower levels of nicotinamide riboside. This in turn raised the question whether this enzyme played a part in combating myopathy.
A study conducted in 2014 established the relationship between myopathy of the mitochondria and nicotinamide riboside. Myopathic mice were administered with nicotinamide riboside. After this supplementation, their mitochondria showed improved performance and these mice were healthier than their control counterparts. It was concluded that nicotinamide riboside fought effects of myopathy.
Nicotinamide riboside and age
Scientists disagree about supplementing the body’s nicotinamide riboside production. Doing so could theoretically offset the age-related low energy production. The end product would be increased longevity as well as general body health improvement.
In another study, nicotinamide riboside was studied to see if the enzyme could alter the human lifespan for the better. The study was performed on rats because they have a cell structure almost similar to that of the human being. A yeast-based approach was applied in this model.
Another similar study was conducted to determine whether this enzyme affected our mental state.
There are still many studies that need to be done before a firm conclusion is established regarding the effects of NAD+ and Niagen on the human body and lifespan.
It’s true there are many supplements that could potentially increase the brain’s alertness. However, only this Vitamin B derivative improves our cognitive ability by improving NAD synthesis in the brain. Therefore, it is possible to improve the brain’s physical strength while reducing its wear and tear. This can only be achieved by supplementing nicotinamide riboside.
What are the side effects of nicotinamide riboside?
In a safety assessment study, a 3,000mg dose was administered in one day—more than ten times the recommended daily dosage. Even at such a high concentration, individuals did not experience the redness and heat from flushing, which is commonly related to high doses of Niagen.
Keep in mind this is a relatively new supplement and there is still a lot of testing needed to determine its effectiveness and side effects on people. If you decide to try it out, it is up to you to stay updated on the latest advances in this supplement. Some physicians believe that if a drug doesn’t have side effects, it probably doesn’t work. That’s not a rule of thumb though. If you want to know more about adding Niagen to your regular diet, discuss this option with your personal physician.
Just as with other supplements, you should consult your doctor before using Live Cell Research’s Niagen to supplement the nicotinamide riboside in your body, especially if you are pregnant or lactating. Not everyone reacts the same way to Niagen, whether it’s related to the effectiveness of the drug or the side effects.
Niagen is currently available from Live Cell Research on their website. This supplement can be ordered from their products page.